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The genetic causes of hair loss as said by Punit Dhawan from Feed the Idiot

Although baldness is commonly associated with men, hair loss can affect anyone, regardless of gender. The amount of hair loss you’ll experience as you get older is largely determined by your genetics. Other variables, such as anxiety, nutrition, and drugs, can also contribute to baldness. Although genetic baldness is irreversible, there are things you can undertake to slow down the process and enhance your hair regeneration capacity. We’ll look at the genetics of balding, debunk a common balding misconception, and discuss methods to slow genetic hair loss in this post.

What is the baldness gene?

Hair loss induced by heredity develops in a predictable pattern known as male pattern baldness (MPB) or female pattern baldness (FPB) (FPB). MPB affects men in their 20s and 30s and manifests itself as an m-shaped recession at the front of the scalp. By the age of 80, almost 80% of males have MPB. Hair loss in the Ludwig pattern, which is a slow regression along the section of your hair, is common in women after menopause. By the age of 80, over half of all women will have female pattern hair. The most prevalent cause of baldness is androgenetic alopecia, which includes MPB and FPB.

Bald gene in men

You may very well have believed that males only inherit the alopecia gene from the maternal grandfather. Even if this isn’t really the case, it does hold some truth. In actuality, the genetic component of male pattern baldness is still a mystery, but it’s assumed to be polygenic, which means it’s caused by multiple genes. The genetic information is stored on 23 pairs of chromosomes in each person. These chromosomes control everything from your eye colour to the length of your baby toe. Your biological sex is determined by one of these pairs of chromosomes, known as the “X” and “Y” chromosomes. Men have one “X” and one “Y” chromosome, whereas women have two “X” chromosomes.

Men acquire their mother’s “X” chromosome and their father’s “Y” chromosome. The AR genes on the “X” chromosome is highly linked to baldness. Individuals with the mutation had more than twice the chance of having MPB than people lacking it, according to a large study of 12,806 men of European descent. This isn’t the only gene that influences whether or not you’ll go bald. Only six of the 63 genes present on the “X” chromosome may play a role in male pattern baldness, according to a 2017 analysis. According to studies, more than 80% of persons who have visible baldness have a father who has likewise lost his hair.

Bald gene in women

Female Pattern Balding or FPB’s genetic link is still undetermined, however it’s believed to underlie a number of genes, similar to MPB. Many females shed their tresses after menopause, while genetics that code for the development of an enzyme called aromatase, which converts testosterone to oestrogen, may play a major role in FPB.

Other causes of Hair Loss

A range of other variables, in addition to heredity, can contribute to hair loss in persons of any gender. Hair loss is common in women after menopause due to hormonal changes, although balding is common in men beginning in early adulthood.

  • Hormonal shifts- Hormone changes cause hair loss in many women following menopause, delivery, and pregnancy. Changes in thyroid hormone levels can cause hair loss in both men and women.
  • Alopecia areata is a kind of alopecia- Alopecia areata is an immunological disorder that develops bald patches.
  • Trichotillomania– Trichotillomania, commonly known as a hair-pulling condition. It is a mental illness that makes you pull out your own hair.
  • Various hairstyles– Tight ponytails and other hairstyles that put tension on your hair can cause traction alopecia, a kind of hair loss. Hair loss can be either permanent or transient.
  • Drugs and dietary supplements. Drugs used to treat the following medical problems, according to the Mayo Clinic, may cause hair loss.
  • Depression
  • Issues with the heart
  • gout
  • Blood pressure that is too high
  • Cancer
  • Arthritis
  • Contraception– Contraception is a method of birth control. It’s possible that stopping birth control tablets will result in temporary hair loss.
  • Radiation therapy– Radiation therapy is a type of treatment that involves the use of radiation to kill unhealthy cells. Hair loss is a typical side effect of radiation therapy, but its commonly employed in cancer treatment. This hair loss is usually just transient.

How to stop Hair loss

Hair loss caused by genetic reasons is irreversible, and there isn’t much you can do about it. There are, however, various techniques to slow things down.

  • Healthy practises of living. Eating a well-balanced diet, getting enough sleep, reducing stress, and exercising on a regular basis can all benefit your general health and hair.
  • Medication that is applied to the skin. Minoxidil (Rogaine) and other topical medicines are frequently used as the first line of treatment. In balding areas, you usually apply these treatments directly to your scalp.
  • Medications taken orally. To treat MPB, your doctor may prescribe finasteride (Propecia), an oral medicine. Finasteride is also a cure for prostrate enlargement.
  • Hair transplant surgery is a procedure that involves the transplanting of hair. Hair transplantation surgeries that relocate hair follicles from one portion of your scalp to thinning areas are known as follicular unit transplantation and follicular unit extraction.
  • Laser therapy is a type of treatment that uses light (red light therapy). If you’re battling with genetic hair loss or chemotherapy-induced hair loss, laser therapy might be able to assist. More research is needed, however, to determine the efficacy of this therapy option.
  • Injections of platelet-rich plasma. Injections of platelet-rich plasma (PRP) may assist encourage hair growth in balding areas. Like laser therapy, this too needs more resaerch.

Conclusion

Genetics and not gender is what affects hair loss. The genetic component of baldness is still unknown, but it is assumed to involve a variety of genes. Medications, laser therapy, and platelet-rich plasma injections may help encourage hair growth in balding areas, despite the fact that genetic hair loss is permanent. Some people also opt for hair transplants to cover their baldness.

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